Syllabus (CHEMISTRY)

Course Type: MAJ-14

Semester: 8

Course Code: BCEMMAJ14C

Course Title: Inorganic Chemistry – V

(L-P-Tu): 4-2-0

Credit: 6

Practical/Theory: Combined

Course Objective: COURSE OBJECTIVE OF MAJOR - 14: The syllabus of Major -14 has been designed to provide the students with thorough understanding of Analytical Chemistry. After successfully completing this syllabus, the students should be able to analyze data for accuracy

Learning Outcome: COURSE OUTCOMES OF MAJOR – 14: CO- 14.1 Understanding and application of Sampling & Errors in Quantitative Analysis. CO- 14.2 Understanding and application of Lambert-Beer’s Law. CO- 14.3 Understanding the basic principles of UV-Vis & IR spectros

THEORY:

Qualitative and quantitative aspects of analysis (10L)

Sampling, evaluation of analytical data, errors, accuracy and precision, methods oftheir expression, normal law of distribution if indeterminate errors, statistical test ofdata; F, Q and t test, rejection of data, and confidence intervals, Detection Limit, Least Square Method.

Optical methods of analysis (15L)

1. Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy and selection rules, validity of Beer-Lambert’s law.

2. UV-Visible Spectrometry: Basic principles

3. Determination of composition of metal complexes using Job’s method of continuous variation and mole ratio method.

4. Infrared Spectrometry: Basic principles

1. Flame Atomic Absorption and Emission Spectrometry: Basic principles of instrumentation (choice of source, monochromator, and detector, choice of flame and Burner designs. Techniques of atomization and sample introduction;

Method of background correction, sources of chemical interferences and their method of removal. Techniques for the quantitative estimation of trace level of metal ions from water samples.

Thermal methods of analysis (5L)

Theory of thermogravimetry (TG), basic principle of instrumentation. Techniques for quantitative estimation of Ca and Mg from their mixture. DTA, DSC.

Electroanalytical methods: (10L)

Classification of electroanalytical methods, basic principle of pH metric, potentiometric, conductometric, amperometric and coulometric titrations. Techniques used for the determination of equivalence points, Dropping Mercury Electrode (DME), Ilkovich Equation, Polarography, Cyclic Voltametry (CV). Techniques used for the determination of pKa values.

Separation techniques (20L)

1. Solvent extraction: Classification, principle and efficiency of the technique.

Mechanism of extraction: extraction by solvation and chelation.

2. Technique of extraction: batch, continuous and counter current extractions.

3. Qualitative and quantitative aspects of solvent extraction: extraction of metal ions from aqueous solution, extraction of organic species from the aqueous and non-aqueous media.

4. Chromatography: Classification, principle and efficiency of the technique.

Mechanism of separation: adsorption, partition & ion exchange.

5. Development of chromatograms: frontal, elution and displacement methods.

6. Qualitative and quantitative aspects of chromatographic methods of analysis:

IC, GLC, GPC, TLC and HPLC.

7. Stereoisomeric separation and analysis: Measurement of optical rotation,calculation of Enantiomeric excess (ee)/ diastereomeric excess (de) ratios anddetermination of enantiomeric composition using NMR, Chiral solvents andchiral shift reagents. Chiral chromatographic techniques using chiral columns(GC and HPLC).

8. Role of computers in instrumental methods of analysis.

READING REFERENCES:

1. Mendham, J., A. I. Vogel’s Quantitative Chemical Analysis 6th Ed., Pearson,2009.
2. Willard, H.H. Et al.: Instrumental Methods of Analysis, 7th Ed. WardsworthPublishing Company, Belmont, California, USA, 1988.
3. Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York,2004.
4. Harris, D.C.: Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman,2016.
5. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age InternationalPublisher,2009.
6. Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis,Cengage Learning India Ed.
7. Mikes, O. Laboratory Hand Book of Chromatographic & Allied Methods, EllesHarwood Series on Analytical Chemistry, John Wiley & Sons, 1979.
8. Ditts, R.V. Analytical Chemistry; Methods of separation, van Nostrand, 1974.

PRACTICALS:

1. Determination of Fe(III) content in cement.

2. Chromatographic separation of Amino acids.

3. Chromatographic separation of Ni & Co using Paper Chromatography.

4. Estimation of Ascorbic Acid in Vitamin-C by Iodometric method.

REFERENCES FOR PRACTICALS:

1. Mendham, J., A. I. Vogel’s Quantitative Chemical Analysis 6th Ed., Pearson, 2009.
2. Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.
3. Harris, D.C. Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman, 2016.
4. Mukherjee, G. N., University Handbook of Undergraduate Chemistry Experiments, University of Calcutta, 2003.

5. Nad, Mahapatra and Ghoshal, An Advance Course in Practical Chemistry, New Central Book Agency, Kolkata.