Syllabus & Course Curriculam
Course Type: MAJ-13
Semester: 7
Course Code: BMCBMAJ07T
Course Title: MEDICAL MICROBIOLOGY
(L-P-Tu): 4-2-0
Credit: 6
Practical/Theory: Combined
Course Objective: 1. To study the nature of normal microbiota of human body, the relationship between human host and different pathogens and the mechanism of pathogenesis. 2. To learn about antimicrobial agents and their mode of actions on pathogens.
Learning Outcome: Upon successful completion of the course the candidate will be able to- 1. Correlate disease symptoms with causative agent, isolate and identify pathogens. 2. Gain knowledge of mechanism of action of antimicrobial drugs and prophylaxis.
MAJOR COURSE 03
COURSE TITLE: MEDICAL MICROBIOLOGY (THEORY)
TOTAL HOURS:60 CREDITS:4
Unit 1.Normal microflora of the human body and host pathogeninteraction
No. of hours :10
Normal microflora of the human body: Importance of normal microflora, normal microflora of skin, throat, gastrointestinal tract, urogenital tract. Host pathogen interaction: Definitions - Infection, Invasion, Pathogenicity, Virulence, Toxigenicity, Carriers and their types, Opportunistic infections, Nosocomial infections. Transmission of infection, Pathophysiologic effects of LPS.
Unit 2.Bacterial diseases No. of hours:10
List of diseases of various organ systems and their causative agents. The following diseases in detail with Symptoms, mode of transmission, prophylaxis and control.
RespiratoryDiseases: Haemophilusinfluenzae, Mycobacterium tuberculosis Gastrointestinal Diseases: Escherichia coli, Salmonella typhi, Vibrio cholerae, Helicobacter pylori Others: Staphylococcus aureus, Bacillus anthracis, Clostridium tetani.
Unit 3. Viral diseases No. of hours:10
List of diseases of various organ systems and their causative agents. The following diseases in detail with Symptoms, mode of transmission, prophylaxis and control; Polio, Hepatitis, Rabies, Dengue, AIDS, Influenza with brief description of swine flu, Ebola, Japanese Encephalitis
Unit 4.Protozoan diseasesNo. of hours:7
List of diseases of various organ systems and their causative agents. The following diseases in detail with Symptoms, mode of transmission, prophylaxis and control Malaria, Kala-azar.
Unit 5. Fungal diseases No. of hours:8
Brief description of each of the following types of mycoses and one representative disease to be studied with respect to transmission, symptoms and prevention Cutaneous mycoses: Tineapedis (Athlete’s foot) Systemic mycoses: Histoplasmosis Opportunistic mycoses: Candidiasis.
Unit 6.Antimicrobial agentsNo. of hours:15
General characteristics and mode of action of different antibacterial agents: Five modes of action with one example each: Inhibitor of nucleic acid synthesis; Inhibitor of cell wall synthesis; Inhibitor of cell membrane function; Inhibitor of protein synthesis; Inhibitor of metabolism Antifungal agents: Mechanism of action of Amphotericin B, Griseofulvin Antiviral agents: Mechanism of action of Amantadine, Acyclovir, Azidothymidine Antibiotic resistance, MDR, XDR, MRSA.
SUGGESTED READING
1. Brooks G.F., Carroll K.C., Butel J.S., Morse S.A. and Mietzner, T.A. (2013) Jawetz, Melnick and Adelberg’s Medical Microbiology. 26th edition. McGraw Hill Publication
2. Ananthanarayan R. and Paniker C.K.J. (2009) Textbook of Microbiology. 8th edition, University Press Publication
3. Goering R., Dockrell H., Zuckerman M. and Wakelin D. (2007) Mims’ Medical Microbiology. 4th edition. Elsevier
4. Willey JM, Sherwood LM, and Woolverton CJ. (2013) Prescott, Harley and Klein’s Microbiology. 9th edition. McGraw Hill Higher Education
COURSE TITLE: MEDICAL MICROBIOLOGY (PRACTICALS)
TOTAL HOURS: 60 CREDITS:2
Basic Features
Undergraduate degree programmes of either 3 or 4-year duration, with multiple entry and exit points and re-entry options, with appropriate certifications such as:
Note: The eligibility condition of doing the UG degree (Honours with Research) is- minimum75% marks to be obtained in the first six semesters.
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