Syllabus (MICROBIOLOGY)

Course Type: MAJ-14

Semester: 8

Course Code: BMCBMAJ08T

Course Title: BIOSTATISTICS

(L-P-Tu): 5-0-1

Credit: 4

Practical/Theory: Theory

Course Objective: 1. To introduce the concept of biostatistics. 2. To learn the application of statistics in biology.

Learning Outcome: Upon successful completion of the course the candidate will be able to- 1. Develop basic knowledge of mathematics as applied to biological phenomenon. 2. Understand different statistical methods used for handling biological data. 3. Develop basic concepts of statistics and its importance.

COURSE TITLE: BIOSTATISTICS (THEORY)

TOTAL HOURS: 60 CREDITS:4

Unit 1. Introduction No. of Hours: 4

Meaning of statistics, aims of statistics, Definitions and limitation of statistics, Need and scope of statistics.

Unit 2. Elementary StatisticsNo. of Hours: 16

Measures of central tendency (Mean, Median and Mode), standard deviation, standard error, Measures of dispersion, Discrete and Continuous random variables, Correlation and Regression, Emphasis on examples from biological sciences, tests of statistical significance and analysis of variance.

Unit 3. Preliminary Notions on samplingNo. of Hours: 12

Sampling Parameters, Difference between sample and population, sampling errors, Difference between parametric and non-parametric statistics, Definition of sample and population, concept of variable, Frequency distribution &its graphical representation

Unit 4. Test of significanceNo. of Hours: 14

Sampling distributions, Standard error, Testing of Hypothesis, Level of significance and Degree of freedom, large sample test based on normal distribution, small sample test basedont-test, z test and f-test, Chi square test.

Unit 5.ModellingNo. of Hours: 14

Mathematical modelling of bacterial growth curve, fermentation, control of microorganism, Differential equation, Set theory, Probability.

SUGGESTED READINGS

1. H. S. Bear: Understanding Calculus, John Wiley and Sons (Second Edition); 2003.

2. E. Batschelet: Introduction to Mathematics for Life Scientists, Springer Verlag, International Student Edition, Narosa Publishing House, New Delhi (1971, 1975)

3. A. Edmondson and D. Druce: Advanced Biology Statistics, Oxford University Press; 1996.

4. W. Danial: Biostatistics: A foundation for Analysis in Health Sciences, John Wiley and Sons Inc; 2004.