Syllabus (ZOOLOGY)

Course Type: MAJ-5

Semester: 4

Course Code: BZOOMAJ05C

Course Title: Parasitology and Immunology

(L-P-Tu): 4-2-0

Credit: 6

Practical/Theory: Combined

Course Objective:

Learning Outcome: At the end of the course, students should be able to: 1. Identify the different types of parasites. 2. Classify parasites causing diseases to humans. 3. Assess the reasons of infections with parasites. 4. Explain the life cycles of various parasites. 5. D

Parasitology and Immunology

Theory - 4 credits

Course Objectives:

1. To provide students with knowledge regarding parasitological terms, types of parasites and host parasite relationship.
2. To provide students with knowledge concerning biological and epidemiological aspects of parasites causing diseases to humans.
3. To enable students to understand the pathogenesis, clinical presentations and complications of parasitic diseases.
4. To enable students to learn diagnosis and know the general outline of treatment, prevention and control of parasitic infections.
5. To provide students with knowledge regarding basic idea of zoonosis and zoonotic diseases. To provide an adequate knowledge about the basic concepts of health and diseases.
6. To provide students with knowledge regarding cells and organs of the immune system.
7. To enable students to understand the innate and adaptive immunity.
8. To provide students with knowledge about antigens and immunoglobulins.
9. To enable students to understand the antigen-antibody interactions and monoclonal antibody production.
10. To provide an adequate knowledge regarding vaccines and autoimmune diseases.

Group A:

Parasitology

Theory

• Introduction to parasitology - Brief introduction of Parasitism, Parasite, Parasitoid and Vectors (mechanical and biological vector), Host parasite relationship.

• Parasitic protists – Parasitic adaptation and study of morphology, life cycle, prevalence, epidemiology, pathogenicity, diagnosis, prophylaxis and treatment of Giardia intestinalis, Trypanosoma gambiense, Leishmania donovani, Plasmodium sp.

• Parasitic helminthes - Parasitic adaptation and study of morphology, life cycle, prevalence, epidemiology, pathogenicity, diagnosis, prophylaxis and treatment of Schistosoma haematobium, Taenia solium, Ascaris lumbricoides, Ancylostoma duodenale, Wuchereria bancrofti.

• Parasitic arthropods - Biology, importance and control of ticks (soft tick Ornithodoros, hard tick Ixodes), lice (Pediculus), and bug (Cimex).

• Basic idea on zoonosis and zoonotic diseases.

Group B:

Immunology

Theory

• Overview of immune system - Basic concepts of health and diseases, Historical perspective of immunology, Cells and organs of the immune system.

• Innate and adaptive immunity - Anatomical barriers, Inflammation, Cell and molecules involved in innate immunity, Adaptive immunity (Cell mediated and humoral).

• Antigens - Antigenicity and immunogenicity, Immunogens, Adjuvants and haptens.

• Immunoglobulins - Structure and functions of different classes of immunoglobulins, Antigen- antibody interactions, Monoclonal antibody production

• Immunology of diseases – Autoimmune diseases (rheumatoid arthrites and Type I diabetes)

• Vaccines - Various types of vaccines. Active and passive immunization (Artificial and natural).
  
  

Practical - 2 credits

Group A: Parasitology

• Study of life stages of Giardia intestinalis, Trypanosoma gambiense, Leishmania donovani, Taenia solium, Ancylostoma duodenale, through permanent slides / micro photographs.

• Study of Pediculus humanus, Xenopsylla cheopis and Cimex lectularius through permanent slides / photographs.

• Study of nematode / cestode parasites from the intestines of poultry bird.

Group B: Immunology

• Demonstration of lymphoid organs.

• Histological study of spleen, thymus and lymph nodes through slides / photographs.

References

Group A: Parasitology

Arora, D.R and Arora, B. (2001). Medical Parasitology, 2^nd Edition.

Noble, E.R. and Noble, G.A. (1982). Parasitology: The Biology of Animal Parasites, 5^th Edition.

Ahmed, N. et al. (2007). Biology of Disease.

Parija, S.C. (2013). Textbook of Medical Parasitology, Protozoology and Helminthology, 4^th Edition.

Ichhpujani, R.L. and Bhatia, R. (2003). Medical Parasitology, 3^rd Edition.

Dailey, D. (1996). Meyer, Olsen and Schmidt's Essentials of Parasitology.

Chatterjee, K.D. (2009). Parasitology: Protozoology and Helminthology. 13^th Edition.

Group B: Immunology

Kuby, J. et al. (2006). Immunology, 6^th Edition.

Abbas, K. et al. (2003). Cellular and Molecular Immunology, 5^th Edition.